Extractive Spectrophotometric Method for Determination of Carvedilol in Tablets
نویسندگان
چکیده
A sensitive and rapid extractive spectrophotometer method has been developed for the assay of carvedilol in pharmaceutical formulations. The method is based on the formation of a chloroform soluble ion-pair complex between carvedilol and bromocresol green in an acidic medium. The complex shows absorption maximum at 415 nm and the system obeys Beer’s law in the concentration range of 5-25 μg/ml. The results obtained by the proposed method were validated statistically and by recovery studies.
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